SCHEMBL2127328

SCHEMBL2127328

COc1cccc(Nc2ccc(C(=O)O)cc2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.71
GFER P55789 2/20 0.71
GAA P10253 1/20 0.71
MTNR1B P49286 6/20 0.68
MTNR1A P48039 4/20 0.68
RAB9A P51151 3/20 0.62
MITF O75030 1/20 0.62
AKR1C3 P42330 4/20 0.61
AKR1C2 P52895 4/20 0.61
MAPT P10636 2/20 0.61
HPGD P15428 1/20 0.61
KMT2A Q03164 3/20 0.57
PKM P14618 2/20 0.57
NLRP3 Q96P20 1/20 0.57
ALDH1A1 P00352 1/20 0.57
TP53 P04637 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CSNK2A1 P68400 1/20 0.57
MEN1 O00255 2/20 0.57
TSHR P16473 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5464421 0.89 NPC1 (0.78) NPC1GFERGAAMTNR1BMTNR1A
SCHEMBL602466 0.88 MTNR1B (0.68) NPC1GFERGAAMTNR1BMTNR1A
SCHEMBL14043859 0.86 HIF1A (0.65) NPC1GFERGAAMTNR1BMTNR1A
SCHEMBL9479511 0.85 MTNR1B (0.68) NPC1GFERGAAMTNR1BMTNR1A
SCHEMBL9479608 0.85 MTNR1B (0.68) NPC1GFERGAAMTNR1BMTNR1A
SCHEMBL1921496 0.85 MTNR1B (0.72) NPC1GAAMTNR1BMTNR1ARAB9A
SCHEMBL14043910 0.84 AKR1C3 (0.60) NPC1GFERGAAMITFAKR1C3
SCHEMBL5465024 0.84 AKR1C3 (0.68) NPC1GFERGAAMTNR1BMTNR1A
SCHEMBL5442673 0.83 CA1 (0.77) NPC1GAARAB9AAKR1C3AKR1C2
SCHEMBL30080139 0.83 MTNR1B (0.65) NPC1GFERGAAMTNR1BMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443742-B1 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-01 EP claimed
US-5476754-A Presensitized; hydrophilic surface on substrate; light sensitive layer containing alkaline water-soluble photocrosslinkable copolycondensed diazo resin FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US claimed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP claimed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP claimed
EP-1249731-B1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORP (JP) 2012-04-25 EP disclosed
EP-1143301-B1 Presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2009-11-11 EP disclosed
US-7316892-B2 Process of preparing planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2008-01-08 US disclosed
US-7220530-B2 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-22 US disclosed
US-7147991-B2 Process of preparing planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2006-12-12 US disclosed
US-20050214685-A1 Process of preparing planographic printing plate Minolta, Konica 2005-09-29 US disclosed
US-20050196700-A1 Process of preparing planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-09-08 US disclosed
EP-1571492-A1 Process of preparing planographic printing plate Konica Minolta Medical & Graphic, Inc. (JP) 2005-09-07 EP disclosed
US-5250393-A Containing diazo resin and alkali metal or ammonium silicate FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US disclosed
EP-0522457-A1 Photosensitive composition Mitsubishi Chemical Corporation (JP) 1993-01-13 EP disclosed
EP-0492959-A1 Method for developing presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1992-07-01 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP disclosed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0397375-A1 Photosensitive composition and photosensitive lithographic printing plate KONICA CORPORATION (JP) 1990-11-14 EP disclosed
US-4181737-A 4-((3-Methoxyphenyl)amino)benzoic acid, a method for treating hyperlipidemia, and compositions thereof THE DOW CHEMICAL COMPANY (US) 1980-01-01 US disclosed