SCHEMBL21274580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22206936	0.87	KDM4E (0.61)	KDM4EPOLBHTTGAAHSD17B10
	SCHEMBL29752804	0.85	KDM4E (0.55)	KDM4EPOLBHTTGAALMNA
	SCHEMBL21274815	0.85	KDM4E (0.55)	KDM4EPOLBHTTGAALMNA
	SCHEMBL13027985	0.85	KDM4E (0.58)	KDM4EPOLBHTTCA12CA1
	SCHEMBL22222148	0.85	CA12 (0.50)	KDM4EPOLBCA12CA1CA2
	SCHEMBL21274816	0.84	LCK (0.50)	KDM4EHTTCA12CA1CA2
	SCHEMBL1498783	0.84	HTT (0.61)	KDM4EHTTGAALMNAHSD17B10
	SCHEMBL70148	0.83	CA12 (0.40)	KDM4EPOLBHTTCA12CA1
	SCHEMBL23906095	0.83	CA12 (0.48)	KDM4EPOLBCA12CA1CA2
	SCHEMBL17184697	0.82	KDM4E (0.51)	KDM4EPOLBHTTGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.