SCHEMBL2127571

SCHEMBL2127571

Nc1ccc(C(=O)N(c2ccccc2)c2ccc(N(C(=O)c3ccc(N)cc3)c3ccccc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
NR3C2 P08235 2/20 0.51
ESR1 P03372 3/20 0.50
ESR2 Q92731 3/20 0.50
NPSR1 Q6W5P4 2/20 0.48
HDAC6 Q9UBN7 2/20 0.45
CYP1B1 Q16678 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
KMT2A Q03164 2/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27521660 0.98 NPSR1 (0.50) ALDH1A1KDM4ETDP1L3MBTL1CYP1A2
SCHEMBL27363399 0.96 NR3C2 (0.55) ALDH1A1KDM4ETDP1L3MBTL1CYP1A2
SCHEMBL9001714 0.88 NR3C2 (0.62) ALDH1A1KDM4ETDP1L3MBTL1MAPT
SCHEMBL9001693 0.88 NPSR1 (0.61) ALDH1A1KDM4ETDP1L3MBTL1MAPT
SCHEMBL1987087 0.85 PARP10 (0.53) ALDH1A1TDP1L3MBTL1CYP3A4MAPT
SCHEMBL11672768 0.84 NR3C2 (0.54) ALDH1A1KDM4ETDP1L3MBTL1CYP1A2
SCHEMBL1003807 0.83 NPSR1 (0.61) ALDH1A1KDM4ETDP1L3MBTL1MAPT
SCHEMBL2113060 0.82 ESR1 (0.69) ALDH1A1MAPTNR3C2ESR1ESR2
SCHEMBL5076006 0.82 POLB (0.58) ALDH1A1TDP1L3MBTL1CYP3A4MAPT
SCHEMBL9789595 0.82 NPSR1 (0.43) ALDH1A1KDM4ETDP1L3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2135218-A None JP disclosed
US-10209554-B2 Method for manufacturing laminated resin black-matrix substrate TORAY INDUSTRIES, INC. (JP) 2019-02-19 US disclosed
EP-2444376-B1 BLACK COMPOSITE PARTICLE, BLACK RESIN COMPOSITION, COLOR FILTER SUBSTRATE AND LIQUID CRYSTAL DISPLAY TORAY INDUSTRIES (JP) 2017-01-25 EP disclosed
US-20160370646-A1 METHOD FOR MANUFACTURING LAMINATED RESIN BLACK-MATRIX SUBSTRATE TORAY INDUSTRIES, INC. (JP) 2016-12-22 US disclosed
US-8329068-B2 Black resin composition, resin black matrix, color filter and liquid crystal display TORAY INDUSTRIES, INC. (JP) 2012-12-11 US disclosed
US-20120128898-A1 BLACK COMPOSITE PARTICLE, BLACK RESIN COMPOSITION, COLOR FILTER SUBSTRATE AND LIQUID CRYSTAL DISPLAY TORAY INDUSTRIES, INC. (JP) 2012-05-24 US disclosed
EP-2444376-A1 BLACK COMPOSITE PARTICLE, BLACK RESIN COMPOSITION, COLOR FILTER SUBSTRATE AND LIQUID CRYSTAL DISPLAY Toray Industries, Inc. (JP) 2012-04-25 EP disclosed
US-20100038606-A1 BLACK RESIN COMPOSITION, RESIN BLACK MATRIX, COLOR FILTER AND LIQUID CRYSTAL DISPLAY TORAY INDUSTRIES, INC. (JP) 2010-02-18 US disclosed
EP-2135900-A1 BLACK RESIN COMPOSITION, RESIN BLACK MATRIX, COLOR FILTER AND LIQUID CRYSTAL DISPLAY Toray Industries, Inc. (JP) 2009-12-23 EP disclosed
JP-H02135218-A CURING AGENT FOR EPOXY RESIN MITSUBISHI HEAVY IND LTD 1990-05-24 JP disclosed