Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127571 | 0.96 | ALDH1A1 (0.52) | NR3C2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL27521660 | 0.94 | NPSR1 (0.50) | NR3C2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL9001714 | 0.88 | NR3C2 (0.62) | NR3C2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL1003807 | 0.88 | NPSR1 (0.61) | NR3C2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL27559939 | 0.85 | CA12 (0.52) | NR3C2TDP1CYP2C19KMT2AMEN1 | |
| SCHEMBL28324842 | 0.84 | NR3C2 (0.58) | NR3C2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL2129928 | 0.84 | PBRM1 (0.58) | NR3C2ALDH1A1L3MBTL1MAPTNPSR1 | |
| SCHEMBL9001693 | 0.83 | NPSR1 (0.61) | NR3C2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL2113010 | 0.82 | ESR1 (0.64) | NR3C2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL28168615 | 0.82 | TDP1 (0.48) | ALDH1A1L3MBTL1TDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057997-C | Process for preparing p-nitroaromatic amides and products thereof | SOLUTIA INC (US) | 2000-11-01 | — | — | CN | disclosed |
| CN-1098402-A | Preparation method and product thereof to the nitryl aromatic acid amides | MONSANTO CO (US) | 1995-02-08 | — | — | CN | disclosed |