Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22963846 | 0.85 | NQO2 (0.39) | POLBPTPN1NQO2NQO1CYP2A6 | |
| SCHEMBL17382483 | 0.76 | HSD17B10 (0.44) | POLBPTPN1NQO2NQO1CYP2A6 | |
| SCHEMBL18810714 | 0.76 | ALDH1A1 (0.42) | POLBNQO2NQO1CYP2A6CYP1B1 | |
| SCHEMBL22963863 | 0.76 | MAPT (0.40) | NQO2NQO1CYP2A6CYP1B1CYP1A1 | |
| SCHEMBL22963859 | 0.76 | CYP1A1 (0.43) | CYP1B1CYP1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL18750614 | 0.75 | HSD17B10 (0.45) | NQO2NQO1CYP2A6CYP1B1CYP1A1 | |
| SCHEMBL22963845 | 0.74 | CYP1A2 (0.41) | CA2CYP1B1CYP1A1MEN1KMT2A | |
| SCHEMBL17037122 | 0.74 | HPRT1 (0.50) | NQO2NQO1CYP2A6CYP1B1CYP1A1 | |
| SCHEMBL30062535 | 0.74 | HSD17B10 (0.52) | NQO2NQO1CYP2A6CYP1B1ALDH1A1 | |
| SCHEMBL13250616 | 0.74 | HSD17B10 (0.52) | NQO2NQO1CYP2A6CYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385035-B2 | Dinaphthothiophene compounds | SAINT LOUIS UNIVERSITY (US) | 2019-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385035-B2 | Dinaphthothiophene compounds | DDT, DNTT, GNPAT | POLB 1390/4885PTPN1 1738/4885ERN1 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.