Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24330941 | 0.97 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL20180557 | 0.97 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL16271048 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL17655912 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL27409850 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL256011 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL14493125 | 0.79 | PTK2 (0.49) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL20725475 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL165333 | 0.79 | SMN1; SMN2 (0.71) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR | |
| SCHEMBL17655966 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4ENPC1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3140302-B1 | MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2019-08-21 | — | — | EP | disclosed |