Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 14/20 | 0.63 |
| ▸ | ESR1 | P03372 | 13/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.63 |
| ▸ | TOP1 | P11387 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16469479 | 0.89 | HRAS (0.61) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL6175427 | 0.88 | KDM4E (0.62) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL7127221 | 0.87 | HRAS (0.57) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL7119707 | 0.87 | HRAS (0.57) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL7125320 | 0.86 | HRAS (0.83) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL7116987 | 0.84 | HRAS (0.57) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL7128037 | 0.84 | HRAS (0.57) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL14002809 | 0.84 | HRAS (0.69) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL6776130 | 0.83 | KDM4E (0.57) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL30469493 | 0.81 | HRAS (0.79) | HRASESR1ESR2TOP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836494-B1 | NEW ALKYLATING AGENTS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2019-08-21 | — | — | EP | disclosed |