Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210015 | 0.99 | PIN1 (0.34) | PIN1NOTUMWNT1GSK3BDYRK1A | |
| SCHEMBL2725507 | 0.99 | PIN1 (0.34) | PIN1NOTUMWNT1GSK3BDYRK1A | |
| SCHEMBL211937 | 0.99 | PIN1 (0.34) | PIN1NOTUMWNT1GSK3BDYRK1A | |
| SCHEMBL211504 | 0.99 | PIN1 (0.34) | PIN1NOTUMWNT1GSK3BDYRK1A | |
| SCHEMBL210362 | 0.99 | PIN1 (0.34) | PIN1NOTUMWNT1GSK3BDYRK1A | |
| SCHEMBL211938 | 0.99 | PIN1 (0.34) | PIN1NOTUMWNT1GSK3BDYRK1A | |
| SCHEMBL211321 | 0.99 | PIN1 (0.34) | PIN1NOTUMWNT1GSK3BDYRK1A | |
| SCHEMBL2837941 | 0.94 | NOTUM (0.33) | NOTUMWNT1GSK3BDYRK1ACTSK | |
| SCHEMBL212135 | 0.94 | ABL1 (0.31) | PIN1WNT1GSK3BDYRK1A | |
| SCHEMBL211557 | 0.94 | ABL1 (0.31) | PIN1WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |