Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | FASN | P49327 | 1/20 | 0.63 |
| ▸ | KAT2A | Q92830 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | LYPLA1 | O75608 | 2/20 | 0.39 |
| ▸ | LYPLA2 | O95372 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947470 | 0.85 | KAT2A (0.59) | POLBFASNKAT2A | |
| SCHEMBL13044449 | 0.79 | POLB (0.58) | POLBFASNKAT2ACYP1A2DAGLA | |
| SCHEMBL10367622 | 0.78 | DAGLA (0.51) | POLBFASNCYP1A2DAGLALYPLA1 | |
| SCHEMBL22571236 | 0.78 | DAGLA (0.51) | POLBFASNCYP1A2DAGLALYPLA1 | |
| SCHEMBL24767125 | 0.78 | POLB (0.61) | POLBFASNKAT2ACYP1A2DAGLA | |
| SCHEMBL7913818 | 0.78 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL17787714 | 0.78 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL7920757 | 0.78 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| Protolichesterinic Acid SCHEMBL7913878 | 0.78 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL6428922 | 0.78 | POLB (1.00) | POLBFASNKAT2ADAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527657-A1 | UNDIFFERENTIATED STEM CELL-REMOVING AGENT, AND METHOD FOR REMOVING UNDIFFERENTIATED STEM CELLS | Keio University (JP) | 2019-08-21 | — | — | EP | disclosed |