Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | FASN | P49327 | 1/20 | 1.00 |
| ▸ | KAT2A | Q92830 | 3/20 | 0.77 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360509 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL7920321 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL7920753 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL13193435 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL7920757 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL3007085 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL17787714 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL6428922 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL7913818 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL6428925 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838889-B1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-05-03 | — | — | EP | disclosed |
| US-9265706-B2 | Lichesterinic acid and the derivatives of same as pigmentation inhibitors | Centre National de la Recherche Scientifique—CNRS (FR) | 2016-02-23 | — | — | US | disclosed |
| US-9265706-B2 | Lichesterinic acid and the derivatives of same as pigmentation inhibitors | Centre National de la Recherche Scientifique—CNRS (FR) | 2016-02-23 | — | — | US | disclosed |
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | UNIVERSITE DE RENNES (FR) | 2015-04-16 | — | — | US | disclosed |
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | UNIVERSITE DE RENNES (FR) | 2015-04-16 | — | — | US | disclosed |
| US-8816101-B2 | Paraconic acids as pigmentation activators | Centre National de la Recherche Scientifique—CNRS (FR) | 2014-08-26 | — | — | US | disclosed |
| WO-2013156738-A2 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2013-10-24 | — | — | WO | disclosed |
| WO-2013155528-A2 | METHODS FOR REDUCING BRAIN INFLAMMATION, INCREASING INSULIN SENSITIVITY, AND REDUCING CERAMIDE LEVELS | FASGEN, INC. (US) | 2013-10-17 | — | — | WO | disclosed |
| EP-0869784-A4 | INHIBITION OF FATTY ACID SYNTHASE AS A MEANS TO REDUCE ADIPOCYTE MASS | UNIV JOHNS HOPKINS (US) | 2001-02-07 | — | — | EP | disclosed |
| US-5981575-A | INDUCING WEIGHT LOSS IN AN ANIMAL BY ADMINISTERING TO THE ANIMAL A COMPOUND WHICH REDUCES FATTY ACID SYNTHASE (FAS) ACTIVITY IN ADIPOCYTES OR LIVER CELLS; 5-SUBSTITUTED 2-OXO-3-METHYLENE-4-FURANCARBOXYLIC ACID | JOHNS HOPKINS UNIVERSITY, THE (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0869784-A1 | INHIBITION OF FATTY ACID SYNTHASE AS A MEANS TO REDUCE ADIPOCYTE MASS | THE JOHNS HOPKINS UNIVERSITY (US) | 1998-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | TYR, MITF, ALDH7A1 | POLB 3467/4885FASN 1495/4885KAT2A 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.