Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21149029 | 0.86 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2TP53KLF5 | |
| SCHEMBL627044 | 0.85 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2TP53KLF5 | |
| SCHEMBL619807 | 0.85 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2TP53KLF5 | |
| SCHEMBL620401 | 0.85 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2TP53KLF5 | |
| SCHEMBL21281399 | 0.85 | MTNR1A (0.48) | RAB9ANPC1MCHR1SMN1; SMN2TP53 | |
| SCHEMBL21281165 | 0.84 | MCHR1 (0.44) | RAB9ANPC1MCHR1SMN1; SMN2KDM4E | |
| SCHEMBL618378 | 0.84 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2TP53KLF5 | |
| SCHEMBL620832 | 0.84 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2TP53KLF5 | |
| SCHEMBL621071 | 0.84 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2TP53KLF5 | |
| SCHEMBL620831 | 0.84 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2TP53KLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552207-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2019-08-21 | — | — | EP | disclosed |