Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21274100 | 1.00 | HRH3 (0.42) | HRH3KCNH2SLC18A3 | |
| SCHEMBL21268806 | 1.00 | HRH3 (0.42) | HRH3KCNH2SLC18A3 | |
| SCHEMBL21274178 | 0.87 | SLC18A3 (0.35) | SLC18A3 | |
| SCHEMBL21274058 | 0.86 | SLC18A3 (0.36) | HRH3KCNH2SLC18A3 | |
| SCHEMBL21274472 | 0.86 | VEGFA (0.37) | KCNH2SLC18A3 | |
| SCHEMBL21274106 | 0.83 | PARP1 (0.35) | HRH3KCNH2SLC18A3 | |
| SCHEMBL21281579 | 0.83 | PARP1 (0.35) | HRH3SLC18A3 | |
| SCHEMBL21281500 | 0.83 | ADRA1A (0.45) | — | |
| SCHEMBL21268787 | 0.81 | PARP1 (0.42) | HRH3SLC18A3 | |
| SCHEMBL21285495 | 0.81 | PARP1 (0.42) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527209-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB Biopharma SPRL (BE) | 2019-08-21 | — | — | EP | disclosed |