Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 11/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21273968 | 0.89 | PARP1 (0.40) | PARP1 | |
| SCHEMBL21268791 | 0.83 | HTR3E (0.43) | PARP1HTR7HTR6HRH3 | |
| SCHEMBL21273992 | 0.81 | PARP1 (0.43) | PARP1 | |
| SCHEMBL21274158 | 0.81 | GBA1 (0.44) | PARP1 | |
| SCHEMBL21274094 | 0.79 | PARP1 (0.50) | PARP1HTR7 | |
| SCHEMBL22802004 | 0.78 | PARP1 (0.46) | PARP1HTR7HRH3 | |
| SCHEMBL21281583 | 0.78 | PARP1 (0.51) | PARP1HTR7NOS3NOS1HRH3 | |
| SCHEMBL21274069 | 0.77 | PARP1 (0.52) | PARP1HTR7HRH3 | |
| SCHEMBL21273928 | 0.76 | PARP1 (0.41) | PARP1 | |
| SCHEMBL21274474 | 0.74 | PIM1 (0.44) | PARP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527209-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB Biopharma SPRL (BE) | 2019-08-21 | — | — | EP | disclosed |