Sugi Predict

Sugi Predict / Compounds / SCHEMBL21281964

SCHEMBL21281964

SCHEMBL21281964

c1ccc(-c2ccc(N(c3ccc4oc5cc(N(c6ccccc6)c6ccccc6)ccc5c4c3)c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.34
▸ HPGD P15428 5/20 0.34
▸ MAPT P10636 4/20 0.34
▸ TSHR P16473 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ GLA P06280 2/20 0.34
▸ HTT P42858 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ ALDH1A1 P00352 4/20 0.33
▸ DUSP3 P51452 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ CASP7 P55210 1/20 0.33
▸ AHR P35869 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ SIGMAR1 Q99720 3/20 0.33
▸ CYP1A1 P04798 2/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14295280 0.95 AHR (0.37) KDM4EHPGDMAPTALDH1A1DUSP3
SCHEMBL15138656 0.95 AHR (0.37) KDM4EHPGDMAPTALDH1A1DUSP3
SCHEMBL14295273 0.95 KDM4E (0.37) KDM4EHPGDMAPTTSHRHSD17B10
SCHEMBL21966511 0.95 KDM4E (0.37) KDM4EHPGDMAPTTSHRHSD17B10
SCHEMBL14295268 0.94 HPGD (0.38) KDM4EHPGDMAPTTSHRHSD17B10
SCHEMBL21968724 0.94 KDM4E (0.38) KDM4EHPGDMAPTTSHRHSD17B10
SCHEMBL14295279 0.94 AHR (0.38) KDM4EHPGDMAPTTSHRHSD17B10
SCHEMBL14295472 0.94 AHR (0.38) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL14295473 0.94 AHR (0.38) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL14295442 0.94 KDM4E (0.38) KDM4EHPGDMAPTTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210028370-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2021-01-28 — — US disclosed
US-20200203623-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-06-25 — — US disclosed
WO-2019190101-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2019-10-03 — — WO disclosed
WO-2019160335-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2019-08-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028370-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREFOR OR51E2, WEE1, SLC39A11 KDM4E 1966/4885HPGD 2616/4885MAPT 2705/4885
US-20200203623-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF GPX1, PIEZO1, ORAI2 KDM4E 2039/4885HPGD 2974/4885MAPT 3035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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