SCHEMBL2128249

SCHEMBL2128249

c1ccc2c(-c3cc(-c4cccc5ccccc45)ncn3)cccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GSK3B P49841 1/20 0.49
CDK5 Q00535 1/20 0.49
CDK5R1 Q15078 1/20 0.49
HTR2C P28335 5/20 0.45
PI4KA P42356 1/20 0.45
PI4K2B Q8TCG2 1/20 0.45
PI4K2A Q9BTU6 1/20 0.45
PI4KB Q9UBF8 1/20 0.45
HTR2A P28223 1/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
MAPT P10636 2/20 0.44
HSD17B10 Q99714 2/20 0.44
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406150 1.00 MEN1 (0.49) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL14725233 0.98 MEN1 (0.47) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL27926692 0.98 MEN1 (0.47) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL18731809 0.91 MIF (0.50) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL30254376 0.87 HTR2C (0.46) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL16805022 0.87 HTR2C (0.46) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL25944030 0.86 PIM1 (0.52) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL13133540 0.84 MEN1 (0.54) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL14725266 0.84 FNTA (0.44) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL14725263 0.83 KMO (0.45) MEN1KMT2AGSK3BCDK5CDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9985223-B2 Iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-29 US disclosed
US-9985223-B2 Iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-29 US disclosed
US-9985223-B2 Iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-29 US disclosed
US-20160064678-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-03 US disclosed
US-20160064678-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-03 US disclosed
US-20160064678-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-03 US disclosed
US-9184398-B2 Light-emitting elements comprising iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-10 US disclosed
US-9184398-B2 Light-emitting elements comprising iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-10 US disclosed
US-9184398-B2 Light-emitting elements comprising iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-10 US disclosed
US-20150108462-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2015-04-23 US disclosed
CN-103570607-A Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2014-02-12 CN disclosed
CN-103579515-A Light-emitting element, light-emitting device, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2014-02-12 CN disclosed
CN-103456899-A Organic material, light-emitting element, light-emitting device, electronic appliance, and lighting device SEMICONDUCTOR ENERGY LAB 2013-12-18 CN disclosed
CN-103450279-A Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2013-12-18 CN disclosed
CN-103168043-A Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2013-06-19 CN disclosed
US-20120098417-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-26 US disclosed
US-20120098417-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-26 US disclosed
US-20120098417-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-26 US disclosed
WO-2012053627-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-04-26 WO disclosed
WO-2012053627-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120098417-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device NR2E3, IGF1R, GRIA1 MEN1 428/4885KMT2A 2385/4885GSK3B 4792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.