Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.41 |
| ▸ | ABL1 | P00519 | 12/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388395 | 1.00 | SRC (0.41) | SRCABL1XDHHCKPIM1 | |
| Hydrochloric Acid SCHEMBL29386515 | 0.98 | SRC (0.40) | SRCABL1XDHHCKPIM1 | |
| Hydrochloric Acid SCHEMBL29386511 | 0.87 | SRC (0.44) | SRCABL1HCKPIM1ADORA1 | |
| Hydrochloric Acid SCHEMBL29388828 | 0.85 | SRC (0.41) | SRCABL1XDHADORA1ADORA3 | |
| Hydrochloric Acid SCHEMBL29388405 | 0.82 | ABL1 (0.43) | SRCABL1XDHADORA1ADORA3 | |
| SCHEMBL2241487 | 0.81 | SRC (0.46) | SRCABL1HCKPIM1ADORA1 | |
| SCHEMBL21282826 | 0.79 | PI4KA (0.50) | SRC | |
| SCHEMBL29385938 | 0.79 | PI4KA (0.50) | SRC | |
| Hydrochloric Acid SCHEMBL29448490 | 0.79 | XDH (0.43) | XDHADORA1ADORA3ADORA2A | |
| Hydrochloric Acid SCHEMBL29389071 | 0.74 | KDM4E (0.39) | SRCHCKPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752506-B1 | PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTIONS | UNIV LIEGE (BE) | 2022-12-14 | — | — | EP | disclosed |
| WO-2019158655-A1 | PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTIONS | UNIVERSITE DE LIEGE (BE) | 2019-08-22 | — | — | WO | disclosed |