Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA7 | P43166 | 5/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060590 | 0.86 | CA1 (0.52) | CA1CA2CA7CA13GLP1R | |
| SCHEMBL19822501 | 0.81 | GAA (0.42) | GLP1RPDE10AGAATDP1 | |
| SCHEMBL11371403 | 0.80 | HTT (0.36) | CA1CA2CA7CA13GLP1R | |
| SCHEMBL13408212 | 0.78 | CA1 (0.38) | CA1CA2CA7CA13 | |
| SCHEMBL21282880 | 0.75 | CA1 (0.46) | CA1CA2CA7CA13PDE10A | |
| SCHEMBL12122378 | 0.72 | CA1 (0.48) | CA1CA2CA7CA13GLP1R | |
| SCHEMBL1064842 | 0.72 | CA1 (0.48) | CA1CA2CA7CA13GLP1R | |
| SCHEMBL11677310 | 0.71 | MEN1 (0.49) | CA1CA2CA7CA13GLP1R | |
| SCHEMBL11890957 | 0.71 | PPARG (0.41) | CA1CA2CA7CA13GLP1R | |
| SCHEMBL1061174 | 0.70 | CA1 (0.49) | CA1CA2CA7CA13LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752506-B1 | PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTIONS | UNIV LIEGE (BE) | 2022-12-14 | — | — | EP | disclosed |
| WO-2020212553-A1 | NEW PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF GRAM-NEGATIVE BACTERIAL INFECTION, CONTAMINATION AND FOULING | Université de Liège (BE) | 2020-10-22 | — | — | WO | disclosed |
| WO-2019158655-A1 | PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTIONS | UNIVERSITE DE LIEGE (BE) | 2019-08-22 | — | — | WO | disclosed |