SCHEMBL2128348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2128595	0.97	KCNQ3 (0.50)	KCNQ3KCNQ2SRCPOLBNPC1
	SCHEMBL2129081	0.92	SRC (0.46)	SRCSMN1; SMN2POLBNAPEPLDPIK3CA
	SCHEMBL30796289	0.92	SRC (0.46)	SRCSMN1; SMN2POLBNAPEPLDPIK3CA
	SCHEMBL2129021	0.89	SRC (0.46)	KCNQ3KCNQ2SRCSMN1; SMN2RAB9A
	SCHEMBL30795834	0.89	SRC (0.47)	SRCPOLBNAPEPLDPIK3CAPIK3CB
	SCHEMBL2129911	0.89	SRC (0.47)	SRCPOLBNAPEPLDPIK3CAPIK3CB
	SCHEMBL2129187	0.88	KCNQ3 (0.51)	KCNQ3KCNQ2SMN1; SMN2NPC1RAB9A
	SCHEMBL2129170	0.87	KCNQ3 (0.63)	KCNQ3KCNQ2NAPEPLDPIK3CAPIK3CB
	SCHEMBL2129653	0.87	SRC (0.46)	SRCNAPEPLDPIK3CAPIK3CBPIK3CD
	SCHEMBL2129643	0.87	SMN1; SMN2 (0.47)	SRCSMN1; SMN2POLBNAPEPLDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.