SCHEMBL2129187

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2129170	0.91	KCNQ3 (0.63)	KCNQ3KCNQ2NAPEPLDKDM4EALDH1A1
	SCHEMBL2128595	0.91	KCNQ3 (0.50)	KCNQ3KCNQ2NAPEPLDMAPTPIK3CG
	SCHEMBL2130173	0.90	PIK3CG (0.43)	KCNQ3KCNQ2NAPEPLDPIK3CGPIK3CA
	SCHEMBL2128348	0.88	KCNQ3 (0.48)	KCNQ3KCNQ2NAPEPLDALDH1A1MAPT
	SCHEMBL2129195	0.88	KCNQ3 (0.51)	KCNQ3KCNQ2NAPEPLDKDM4EALDH1A1
	SCHEMBL2129789	0.86	KCNQ3 (0.47)	KCNQ3KCNQ2PIK3CA
	SCHEMBL2129573	0.85	MEN1 (0.52)	KCNQ3KCNQ2NAPEPLDKDM4EALDH1A1
	SCHEMBL2129798	0.85	KCNQ3 (0.50)	KCNQ3KCNQ2NAPEPLDKDM4EALDH1A1
	SCHEMBL30795711	0.85	KCNQ3 (0.50)	KCNQ3KCNQ2NAPEPLDKDM4EALDH1A1
	SCHEMBL2129065	0.84	NAPEPLD (0.42)	NAPEPLDPIK3CGPIK3CAAKT1PIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.