SCHEMBL2128362

SCHEMBL2128362

FC(F)(F)Cc1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.52
CYP2C19 P33261 2/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2D6 P10635 2/20 0.48
TDP1 Q9NUW8 2/20 0.47
ACP3 P15309 1/20 0.46
HPGD P15428 3/20 0.42
MEN1 O00255 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KMT2A Q03164 2/20 0.42
HTT P42858 1/20 0.42
CA2 P00918 1/20 0.42
MAPT P10636 1/20 0.42
CYP2A6 P11509 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NR3C1 P04150 1/20 0.40
NR3C2 P08235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2754934 0.83 CYP2D6 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL17288656 0.83 CYP2D6 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL17488720 0.83 CYP2D6 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL17288445 0.80 CYP1A2 (0.46) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL5255388 0.79 CYP1A2 (0.48) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL14554294 0.79 TDP1 (0.44) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL17224808 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL11586023 0.78 CYP2D6 (0.53) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL31675157 0.78 CYP2D6 (0.53) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL11717665 0.78 IDO1 (0.38) TDP1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233864-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE 凸版印刷株式会社 2023-12-07 WO disclosed
WO-2023132318-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE 凸版印刷株式会社 2023-07-13 WO disclosed
CN-110437046-B Fluorine atom-containing polymer and field of use thereof 日产化学工业株式会社 2022-08-16 CN disclosed
WO-2021108683-A1 COVALENT RAS INHIBITORS AND USES THEREOF Revolution Medicines, Inc. (US) 2021-06-03 WO disclosed
CN-107406584-B Fluorine atom-containing polymer and field of use thereof 日产化学工业株式会社 2020-06-09 CN disclosed
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
CN-105481738-B A kind of method of the copper catalysis synthesis trifluoroethyl thioether of aromatic hydrocarbons 2,2,2 福州大学 2018-03-20 CN disclosed
US-20180030200-A1 FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-01 US disclosed
EP-3263622-A1 FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME Nissan Chemical Industries, Ltd. (JP) 2018-01-03 EP disclosed
EP-1167366-A1 AMINE DERIVATIVES Sankyo Company, Limited (JP) 2002-01-02 EP disclosed
EP-1130584-A2 Dipyrromethene-metal chelate compound and optical recording medium using thereof Mitsui Chemicals, Inc. (JP) 2001-09-05 EP disclosed
EP-0822544-B1 Optical recording medium MITSUI CHEMICALS INC (JP) 2001-01-03 EP disclosed
US-6162520-A Optical recording medium and dipyrromethene metal chelate compound for use therein MITSUI CHEMICALS, INC. (JP) 2000-12-19 US disclosed
US-6060606-A OPTICAL RECORDING MEDIUM HAVING AT LEAST A RECORDING LAYER AND A REFLECTIVE LAYER ON A SUBSTRATES; HIGH DENSITY, COMPACT DISKS MITSUI CHEMICALS, INC. (JP) 2000-05-09 US disclosed
EP-0755052-B1 Optical recording medium MITSUI CHEMICALS INC (JP) 1999-11-17 EP disclosed
EP-0903733-A2 Optical recording medium and dipyrromethene metal chelate compound for use therein Mitsui Chemicals, Inc. (JP) 1999-03-24 EP disclosed
EP-0881636-A1 Optical recording medium Mitsui Chemicals, Inc. (JP) 1998-12-02 EP disclosed
EP-0822544-A1 Optical recording medium MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-02-04 EP disclosed
EP-0755052-A2 Optical recording medium MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 CYP1A2 360/4885CYP2C19 575/4885CYP2C9 443/4885
US-20180030200-A1 FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME AFF2, AFF1, AFF4 CYP1A2 3504/4885CYP2C19 3604/4885CYP2C9 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.