SCHEMBL212843

SCHEMBL212843

Cn1cccc1/C=N/OS(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
MAPT P10636 8/20 0.42
ALDH1A1 P00352 7/20 0.42
KMT2A Q03164 6/20 0.42
TDP1 Q9NUW8 4/20 0.42
GAA P10253 4/20 0.42
KDM4E B2RXH2 3/20 0.42
GFER P55789 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.41
MAPK1 P28482 1/20 0.39
RAB9A P51151 7/20 0.39
MEN1 O00255 5/20 0.39
XBP1 P17861 3/20 0.38
MPI P34949 3/20 0.38
NPSR1 Q6W5P4 3/20 0.38
HTT P42858 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212844 1.00 CA1 (0.46) CA1CA2TRIM24TRIM33MAPT
SCHEMBL212181 0.76 ALDH1A1 (0.39) MAPTALDH1A1KMT2ATDP1KDM4E
SCHEMBL212180 0.76 ALDH1A1 (0.39) MAPTALDH1A1KMT2ATDP1KDM4E
SCHEMBL17256866 0.75 SMN1; SMN2 (0.34) MAPTALDH1A1KMT2ATDP1GAA
SCHEMBL17256869 0.75 SMN1; SMN2 (0.34) MAPTALDH1A1KMT2ATDP1GAA
SCHEMBL214809 0.74 MAPT (0.46) CA1CA2MAPTALDH1A1KMT2A
SCHEMBL214810 0.74 MAPT (0.46) CA1CA2MAPTALDH1A1KMT2A
SCHEMBL212415 0.72 KMT2A (0.51) MAPTALDH1A1KMT2ATDP1GAA
SCHEMBL212416 0.72 KMT2A (0.51) MAPTALDH1A1KMT2ATDP1GAA
SCHEMBL213297 0.72 MAPT (0.47) MAPTALDH1A1KMT2ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8541509-B2 Polymers functionalized with protected oxime compounds BRIDGESTONE CORPORATION (JP) 2013-09-24 US disclosed
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US disclosed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed