Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 20/20 | 0.77 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.77 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21285724 | 0.96 | EP300 (0.76) | EP300CREBBPCYP2C8CYP2D6CYP2C9 | |
| SCHEMBL21285906 | 0.93 | EP300 (0.78) | EP300CREBBP | |
| SCHEMBL21285863 | 0.92 | EP300 (0.78) | EP300CREBBP | |
| SCHEMBL21285905 | 0.92 | EP300 (0.80) | EP300CREBBP | |
| SCHEMBL21285970 | 0.91 | EP300 (0.79) | EP300CREBBP | |
| SCHEMBL21285969 | 0.91 | EP300 (0.78) | EP300CREBBPCYP2C8CYP2D6CYP2C9 | |
| SCHEMBL21285926 | 0.91 | EP300 (0.78) | EP300CREBBPCYP2C8CYP2D6CYP2C9 | |
| SCHEMBL29322285 | 0.90 | EP300 (0.75) | EP300CREBBP | |
| SCHEMBL29324254 | 0.90 | EP300 (0.68) | EP300CREBBP | |
| SCHEMBL29324272 | 0.90 | EP300 (0.70) | EP300CREBBPCYP2C8CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752497-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2019161162-A1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2019-08-22 | — | — | WO | disclosed |