SCHEMBL29322285

SCHEMBL29322285

Cc1ccc(CCNCC(C(=O)Nc2ccc(-c3cnn(C)c3)cn2)c2ccccc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 20/20 0.75
CREBBP Q92793 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21285846 0.92 EP300 (0.76) EP300CREBBP
SCHEMBL21285944 0.92 EP300 (0.77) EP300CREBBP
SCHEMBL21285907 0.92 EP300 (0.76) EP300CREBBP
SCHEMBL21286010 0.90 EP300 (0.77) EP300CREBBP
SCHEMBL21285925 0.87 EP300 (0.78) EP300CREBBP
SCHEMBL23242106 0.86 EP300 (1.00) EP300CREBBP
SCHEMBL21285900 0.86 EP300 (1.00) EP300CREBBP
SCHEMBL30011384 0.86 EP300 (1.00) EP300CREBBP
SCHEMBL21286119 0.86 EP300 (1.00) EP300CREBBP
SCHEMBL21285724 0.85 EP300 (0.76) EP300CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752497-B1 P300/CBP HAT INHIBITORS CONSTELLATION PHARMACEUTICALS INC (US) 2024-07-17 EP disclosed