Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | GABBR2 | O75899 | 6/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21286098 | 1.00 | TAAR1 (0.60) | TAAR1ADRB2GABBR2GABBR1LMNA | |
| SCHEMBL1032332 | 1.00 | TAAR1 (0.60) | TAAR1ADRB2GABBR2GABBR1LMNA | |
| Hydrochloric Acid SCHEMBL1570094 | 0.98 | TAAR1 (0.58) | TAAR1ADRB2GABBR2GABBR1LMNA | |
| SCHEMBL11493598 | 0.94 | TAAR1 (0.54) | TAAR1ADRB2GABBR2GABBR1LMNA | |
| SCHEMBL11487785 | 0.88 | TAAR1 (0.48) | TAAR1ADRB2GABBR2GABBR1LMNA | |
| SCHEMBL3006604 | 0.87 | TAAR1 (0.75) | TAAR1NFKB1TSHRAOC3 | |
| Hydrochloric Acid SCHEMBL6564727 | 0.85 | TAAR1 (0.71) | TAAR1NFKB1TSHRAOC3 | |
| Hydrochloric Acid SCHEMBL5877955 | 0.83 | TAAR1 (0.62) | TAAR1ADRB2SMN1; SMN2 | |
| SCHEMBL6222745 | 0.82 | ADRB2 (0.52) | TAAR1ADRB2GABBR2GABBR1LMNA | |
| SCHEMBL11566936 | 0.79 | ADRB2 (0.48) | TAAR1ADRB2GABBR2GABBR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752497-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2021021893-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |
| WO-2019161162-A1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2019-08-22 | — | — | WO | disclosed |