SCHEMBL21287540

SCHEMBL21287540

N=C1CCCCC12CCNCC2

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22495622 0.73 CRBN (0.39) CRBN
SCHEMBL29749879 0.65 CRBN (0.50) CRBN
SCHEMBL2169285 0.65 CRBN (0.41) CRBN
SCHEMBL7382981 0.65 SIGMAR1 (0.54)
Hydrochloric Acid SCHEMBL6975774 0.64 CRBN (0.39) CRBN
SCHEMBL13647678 0.64
SCHEMBL21224581 0.62 CRBN (0.38) CRBN
SCHEMBL22958822 0.61 CRBN (0.37) CRBN
SCHEMBL3359605 0.60
SCHEMBL23009445 0.60 CRBN (0.36) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019158019-A1 PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海青煜医药科技有限公司 2019-08-22 WO disclosed