Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763164 | 0.88 | USP2 (0.36) | DRD4OPRM1USP2 | |
| SCHEMBL23763168 | 0.85 | — | — | |
| SCHEMBL18497943 | 0.85 | DRD4 (0.35) | DRD4OPRM1USP2 | |
| SCHEMBL19502967 | 0.79 | NCF1 (0.34) | — | |
| SCHEMBL26050031 | 0.78 | USP2 (0.32) | USP2 | |
| SCHEMBL14089970 | 0.78 | USP2 (0.32) | USP2 | |
| SCHEMBL25775252 | 0.78 | USP2 (0.32) | USP2 | |
| SCHEMBL24294399 | 0.78 | USP2 (0.32) | USP2 | |
| SCHEMBL17888424 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL27288558 | 0.76 | OPRL1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753941-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Blueray Biopharma Co., Ltd. (CN) | 2020-12-23 | — | — | EP | disclosed |
| WO-2019158019-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海青煜医药科技有限公司 | 2019-08-22 | — | — | WO | disclosed |