Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.77 |
| ▸ | ITGAV | P06756 | 19/20 | 0.77 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.77 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.64 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.64 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23083106 | 0.92 | ITGB3 (0.75) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL24759380 | 0.92 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL23083026 | 0.92 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL23082960 | 0.91 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL12010935 | 0.91 | ITGB3 (0.81) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL23083174 | 0.89 | ITGB3 (0.70) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL330242 | 0.89 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL23083065 | 0.89 | ITGB3 (0.69) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6418086 | 0.88 | ITGB3 (0.78) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6418095 | 0.88 | ITGB3 (0.78) | ITGB3ITGAVITGA2BITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019161213-A1 | TRIALKYNE LINKING AGENTS AND METHODS OF USE | Arrowhead Pharmaceuticals, Inc. (US) | 2019-08-22 | — | — | WO | disclosed |