SCHEMBL21291348

SCHEMBL21291348

c1ccc(-c2cc(-n3c4ccccc4c4cc(-n5c6ccccc6c6ccccc65)ccc43)nc3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.50
KDM4E B2RXH2 7/20 0.46
ALDH1A1 P00352 6/20 0.46
HPGD P15428 4/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 3/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
ATM Q13315 1/20 0.41
ACACA Q13085 2/20 0.38
RAC2 P15153 1/20 0.37
RAC3 P60763 1/20 0.37
CDC42 P60953 1/20 0.37
RAC1 P63000 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
LTB4R Q15722 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877124 0.92 EGFR (0.43) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL14979344 0.90 EGFR (0.48) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL12691041 0.89 EGFR (0.45) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL14979609 0.88 EGFR (0.47) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL16706428 0.87 EGFR (0.46) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL12014899 0.87 EGFR (0.56) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL19618525 0.86 EGFR (0.41) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL24752968 0.86 EGFR (0.38) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL15682599 0.85 EGFR (0.44) EGFRKDM4EALDH1A1HPGDLMNA
SCHEMBL16706427 0.85 EGFR (0.44) EGFRKDM4EALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190259947-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2019-08-22 US disclosed