Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | RAC2 | P15153 | 1/20 | 0.33 |
| ▸ | RAC3 | P60763 | 1/20 | 0.33 |
| ▸ | CDC42 | P60953 | 1/20 | 0.33 |
| ▸ | RAC1 | P63000 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21291348 | 0.92 | EGFR (0.50) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL19507671 | 0.89 | EGFR (0.52) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL22868909 | 0.88 | EGFR (0.41) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL12691041 | 0.86 | EGFR (0.45) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL12014926 | 0.86 | EGFR (0.47) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL26385734 | 0.85 | KDM4E (0.40) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL14233338 | 0.85 | KDM4E (0.40) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL24752968 | 0.83 | EGFR (0.38) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL14979344 | 0.82 | EGFR (0.48) | EGFRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL17642208 | 0.81 | L3MBTL1 (0.47) | KDM4EALDH1A1HTTMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10186669-B2 | Organic electroluminescent compound and an organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) | 2019-01-22 | — | — | US | disclosed |
| US-9997723-B2 | Organic electroluminescent compound and an organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) | 2018-06-12 | — | — | US | disclosed |
| US-9997723-B2 | Organic electroluminescent compound and an organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) | 2018-06-12 | — | — | US | disclosed |
| US-20170148998-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2017-05-25 | — | — | US | disclosed |
| US-20170148998-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10186669-B2 | Organic electroluminescent compound and an organic electroluminescent device comprising the same | OR10J3, OPA1, ODC1 | EGFR 2485/4885KDM4E 885/4885ALDH1A1 542/4885 |
| US-20170148998-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | OR10J3, OPA1, ODC1 | EGFR 2485/4885KDM4E 885/4885ALDH1A1 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.