Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938090 | 0.83 | NR1H4 (0.51) | NR1H4SMN1; SMN2S1PR1RAB9ANPC1 | |
| SCHEMBL31375567 | 0.81 | NPC1 (0.53) | NR1H4SMN1; SMN2S1PR1RAB9ANPC1 | |
| SCHEMBL16242134 | 0.81 | NPC1 (0.46) | NR1H4SMN1; SMN2S1PR1NPC1NFKB1 | |
| SCHEMBL77636 | 0.81 | NR1H4 (0.57) | NR1H4SMN1; SMN2NOTUMS1PR1RAB9A | |
| SCHEMBL21380545 | 0.80 | RAB9A (0.56) | SMN1; SMN2S1PR1RAB9ANPC1NFKB1 | |
| SCHEMBL21339852 | 0.78 | HDAC4 (0.42) | NR1H4SMN1; SMN2S1PR1RAB9ANPC1 | |
| SCHEMBL31375512 | 0.78 | HDAC4 (0.45) | NR1H4SMN1; SMN2S1PR1RAB9ANPC1 | |
| SCHEMBL8657046 | 0.75 | MAPT (0.57) | NOTUMRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL22353180 | 0.74 | HDAC4 (0.45) | NR1H4SMN1; SMN2S1PR1RAB9ANPC1 | |
| SCHEMBL1473020 | 0.73 | NR1H4 (1.00) | NR1H4SMN1; SMN2NOTUMS1PR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958431-B9 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | MONSANTO TECHNOLOGY LLC (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-2958431-B1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | MONSANTO TECHNOLOGY LLC (US) | 2019-11-20 | — | — | EP | disclosed |