Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | LGMN | Q99538 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17651382 | 0.83 | MAPT (0.66) | MAPTGAASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL30458638 | 0.83 | MAPT (0.66) | MAPTGAASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL19174694 | 0.74 | MAPT (0.54) | MAPTGAASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL8152649 | 0.74 | MAPK1 (0.77) | MAPTGAASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL9899360 | 0.74 | MAPT (0.54) | MAPTGAASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL12875481 | 0.73 | CYP2A13 (0.50) | MAPTGAASMN1; SMN2MAPK1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL1164065 | 0.72 | CYP2A13 (0.49) | MAPTGAASMN1; SMN2KDM4EALDH3A1 | |
| SCHEMBL78364 | 0.71 | MAPT (1.00) | MAPTGAASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL29715972 | 0.71 | MAPT (1.00) | MAPTGAASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL19608840 | 0.71 | DRD2 (0.50) | MAPTGAASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204453-B1 | LOW MOLECULAR WEIGHT GRAFT POLYMER FOR SCALE INHIBITOR | HERCULES LLC (US) | 2019-08-28 | — | — | EP | claimed |