Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 11/20 | 0.72 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.72 |
| ▸ | MET | P08581 | 5/20 | 0.61 |
| ▸ | IGF1R | P08069 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | AXL | P30530 | 1/20 | 0.60 |
| ▸ | MERTK | Q12866 | 1/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.58 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.57 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL19511903 | 0.97 | PTK2B (0.67) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL19511965 | 0.93 | PTK2B (0.62) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL19512004 | 0.93 | PTK2B (0.70) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL19511905 | 0.90 | PTK2B (0.66) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL19511548 | 0.88 | PTK2B (0.73) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL19511988 | 0.86 | PTK2B (0.77) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL19511441 | 0.85 | PTK2B (0.80) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL19511748 | 0.85 | PTK2B (0.78) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL198979 | 0.83 | PTK2B (1.00) | PTK2BPTK2METIGF1RKDR | |
| SCHEMBL19511587 | 0.83 | SYK (0.76) | PTK2BPTK2METIGF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239147-B1 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2019-08-28 | — | — | EP | claimed |