Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 3/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19739012 | 0.80 | PRKCQ (0.55) | PRKCQMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL16793205 | 0.80 | PRKCQ (0.59) | PRKCQKDM4CMAPTL3MBTL1TDP1 | |
| SCHEMBL16793163 | 0.78 | PRKCQ (0.55) | PRKCQMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL15540361 | 0.77 | MAPT (0.58) | PRKCQMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL16797143 | 0.77 | MAPT (0.53) | PRKCQKDM4CMAPTL3MBTL1TDP1 | |
| SCHEMBL29677817 | 0.77 | KAT2B (0.48) | PRKCQKDM4CMAPTL3MBTL1TDP1 | |
| SCHEMBL15540171 | 0.77 | KAT2B (0.48) | PRKCQKDM4CMAPTL3MBTL1TDP1 | |
| SCHEMBL3449318 | 0.76 | PGK1 (0.48) | MAPTL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15740633 | 0.76 | MAPT (0.53) | PRKCQMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL19742063 | 0.76 | MAPT (0.43) | PRKCQMAPTL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080126-B1 | PURINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL (BE) | 2019-08-28 | — | — | EP | disclosed |