Metacresol

Metacresol

SCHEMBL21291795

Cc1cc(O)ccc1Br.Cc1cccc(O)c1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.65
CYP1A2 P05177 3/20 0.54
CYP2C19 P33261 3/20 0.54
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 3/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
RAPGEF4 Q8WZA2 1/20 0.41
ESR2 Q92731 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49999 0.85
Metacresol SCHEMBL28155447 0.81 ACHE (0.90) ACHECYP1A2CYP2C19ALDH1A1MAPK1
Metacresol SCHEMBL10736 0.81
Metacresol SCHEMBL11437600 0.81 ACHE (1.00) ACHECYP1A2CYP2C19ALDH1A1MAPK1
Metacresol SCHEMBL2314567 0.81 ACHE (1.00) ACHECYP1A2CYP2C19ALDH1A1MAPK1
Metacresol SCHEMBL9774388 0.81 ACHE (1.00) ACHECYP1A2CYP2C19ALDH1A1MAPK1
Metacresol SCHEMBL29352064 0.81
Metacresol SCHEMBL28289101 0.79 ACHE (0.85) ACHECYP1A2CYP2C19ALDH1A1MAPK1
Metacresol SCHEMBL7177747 0.79
Metacresol SCHEMBL10008998 0.79 ACHE (0.94) ACHECYP1A2CYP2C19ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3162786-B1 METHOD FOR PRODUCING 4-ISOPROPYL-3-METHYLPHENOL OSAKA KASEI CO LTD (JP) 2019-08-28 EP claimed