Fluoride

Fluoride

SCHEMBL21291892

F.O=C(F)c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.55
CES2 O00748 5/20 0.55
TSHR P16473 3/20 0.55
ALDH1A1 P00352 3/20 0.55
DAO P14920 1/20 0.55
NAPRT Q6XQN6 1/20 0.55
TDP1 Q9NUW8 4/20 0.50
CYP3A4 P08684 2/20 0.50
MAPT P10636 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
HSD17B10 Q99714 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA9 Q16790 2/20 0.50
POLB P06746 1/20 0.50
PARP1 P09874 1/20 0.50
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27434180 1.00 CES1 (0.55) CES1CES2TSHRALDH1A1DAO
SCHEMBL7378830 0.97 CES1 (0.58) CES1CES2TSHRALDH1A1DAO
SCHEMBL295618 0.97
Hydrochloric Acid SCHEMBL27436699 0.94 CES1 (0.55) CES1CES2TSHRALDH1A1DAO
Hydrochloric Acid SCHEMBL27691884 0.94 CES1 (0.55) CES1CES2TSHRALDH1A1DAO
Hydrochloric Acid SCHEMBL27901056 0.92 CES1 (0.52) CES1CES2TSHRALDH1A1DAO
Calcium Chloride SCHEMBL27901055 0.89 CES1 (0.50) CES1CES2TSHRALDH1A1DAO
Acetone SCHEMBL27854896 0.89 CES1 (0.54) CES1CES2TSHRALDH1A1DAO
SCHEMBL10887198 0.85 CES1 (0.54) CES1CES2TSHRALDH1A1DAO
Trifluoromethylbenzene SCHEMBL21291903 0.84 ALDH1A1 (0.58) CES1CES2TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3529232-A1 SULPHAMIC ACID DERIVATIVES AND PRODUCTION METHODS THEREOF Hydro-Québec (CA) 2019-08-28 EP disclosed