SCHEMBL21292988

SCHEMBL21292988

c1ccc(-c2ccc3sc4ccc(-c5ccccc5)c(-c5ccc(C6(c7ccccc7)c7ccccc7-c7ccccc76)cc5)c4c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.38
WEE1 P30291 1/20 0.38
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PDK2 Q15119 2/20 0.35
LIMK1 P53667 2/20 0.34
PIM3 Q86V86 1/20 0.34
POLB P06746 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29015679 0.85 LIMK1 (0.39) CHEK1WEE1PDK2LIMK1PIM3
SCHEMBL15293756 0.79 PDK2 (0.38) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL283913 0.79 LIMK1 (0.38) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL29360070 0.79 LIMK1 (0.38) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL18086215 0.78 GPR3 (0.38) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL24041689 0.78 MEN1 (0.39) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL24041597 0.78 KDM4E (0.33) CHEK1WEE1MEN1KMT2AKDM4E
SCHEMBL18326015 0.77 PIM3 (0.35) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL438625 0.77 LIMK1 (0.39) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL21904615 0.77 MEN1 (0.35) CHEK1WEE1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10734594-B2 Light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-08-04 US disclosed
US-20190267564-A1 LIGHT-EMITTING ELEMENT SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-08-29 US disclosed