SCHEMBL21294032

SCHEMBL21294032

C=Cc1cccc[n+]1C(C)CCS(=O)(=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.44
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
CTDSP1 Q9GZU7 2/20 0.34
MAPT P10636 1/20 0.34
RXFP1 Q9HBX9 1/20 0.32
PABPC1 P11940 1/20 0.32
EIF4H Q15056 1/20 0.32
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21326533 1.00 HDAC8 (0.44) HDAC8KDM4EALDH1A1CTDSP1MAPT
SCHEMBL30800888 1.00 HDAC8 (0.44) HDAC8KDM4EALDH1A1CTDSP1MAPT
SCHEMBL5074539 0.74 HDAC8 (0.42) HDAC8
SCHEMBL7057931 0.73 HDAC8 (0.44) HDAC8KDM4EALDH1A1CTDSP1MAPT
Sulfuric Acid SCHEMBL11856466 0.72 HDAC8 (0.78) HDAC8KDM4EALDH1A1CTDSP1MAPT
Sulfuric Acid SCHEMBL30240018 0.72 HDAC8 (0.78) HDAC8KDM4EALDH1A1CTDSP1MAPT
SCHEMBL18148998 0.71 ALDH1A1 (0.48) HDAC8KDM4EALDH1A1CTDSP1MAPT
SCHEMBL29356904 0.71 ALDH1A1 (0.48) HDAC8KDM4EALDH1A1CTDSP1MAPT
SCHEMBL31506477 0.70 HDAC8 (0.47) HDAC8
SCHEMBL11411755 0.70 HDAC8 (0.47) HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4371653-A1 FABRICATION OF FILTRATION MEMBRANES Trustees of Tufts College (US) 2024-05-22 EP claimed
US-20190262781-A1 FABRICATION OF FILTRATION MEMBRANES TRUSTEES OF TUFTS COLLEGE 2019-08-29 US claimed
US-12233383-B2 Fabrication of filtration membranes TRUSTEES OF TUFTS COLLEGE (US) 2025-02-25 US disclosed
EP-4371653-A1 FABRICATION OF FILTRATION MEMBRANES Trustees of Tufts College (US) 2024-05-22 EP disclosed
US-20240149225-A1 FABRICATION OF FILTRATION MEMBRANES TRUSTEES OF TUFTS COLLEGE 2024-05-09 US disclosed
US-11896937-B2 Fabrication of filtration membranes TRUSTEES OF TUFTS COLLEGE (US) 2024-02-13 US disclosed
US-20190262781-A1 FABRICATION OF FILTRATION MEMBRANES TRUSTEES OF TUFTS COLLEGE 2019-08-29 US disclosed