Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168891 | 0.93 | MAPT (0.61) | CYP1A1CYP1B1MAPTALDH1A1MEN1 | |
| SCHEMBL13168892 | 0.92 | MAPT (0.60) | CYP1A1CYP1B1MAPTALDH1A1MEN1 | |
| SCHEMBL13168896 | 0.89 | MAPT (0.57) | CYP1A1CYP1B1MAPTALDH1A1MEN1 | |
| SCHEMBL13168939 | 0.89 | MAPT (0.57) | CYP1A1CYP1B1MAPTALDH1A1MEN1 | |
| SCHEMBL1712815 | 0.89 | POLB (0.55) | CYP1A1CYP1B1KDM4EMAPTALDH1A1 | |
| SCHEMBL13168899 | 0.89 | MAPT (0.57) | CYP1A1CYP1B1MAPTALDH1A1MEN1 | |
| SCHEMBL13168894 | 0.85 | MAPT (0.58) | CYP1A1CYP1B1MAPTALDH1A1MEN1 | |
| SCHEMBL13186141 | 0.85 | MAPT (0.52) | CYP1A1CYP1B1MAPTALDH1A1MEN1 | |
| SCHEMBL79457 | 0.84 | MAPT (0.79) | CYP1A1CYP1B1KDM4EMAPTALDH1A1 | |
| SCHEMBL27892982 | 0.84 | MAPT (0.79) | CYP1A1CYP1B1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262252-A1 | OIL BASED COMPOSITION AND OIL BASED COSMETIC | SHISEIDO COMPANY, LTD. (JP) | 2019-08-29 | — | — | US | disclosed |