SCHEMBL79457

SCHEMBL79457

COc1ccc(C=CC(=O)O)c(OC)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.79
ALDH1A1 P00352 3/20 0.79
MEN1 O00255 3/20 0.79
KMT2A Q03164 3/20 0.79
NPC1 O15118 2/20 0.71
RAB9A P51151 2/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
TNFRSF1A P19438 1/20 0.70
CYP1A1 P04798 5/20 0.68
CYP1A2 P05177 5/20 0.68
CYP1B1 Q16678 4/20 0.68
LY96 Q9Y6Y9 1/20 0.67
MAPK1 P28482 2/20 0.65
HPGD P15428 2/20 0.63
LMNA P02545 1/20 0.63
CHRNA7 P36544 1/20 0.62
GAA P10253 1/20 0.61
BACE1 P56817 1/20 0.60
KDM4E B2RXH2 1/20 0.60
TP53 P04637 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79456 1.00 MAPT (0.79) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL29449851 1.00 MAPT (0.79) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL27892982 1.00 MAPT (0.79) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL27858760 0.98 MAPT (0.77) MAPTALDH1A1MEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL15299858 0.98 MAPT (0.77) MAPTALDH1A1MEN1KMT2ANPC1
Cinnamic Acid SCHEMBL16271170 0.91 CYP1A1 (0.71) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL10468808 0.91 MAPT (0.85) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL10468807 0.91 MAPT (0.85) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL10661702 0.90 MAPT (0.69) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL6782178 0.90 MAPT (0.69) MAPTALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
WO-2025081932-A1 RETINOL DERIVATIVE OR SALT THEREOF, AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 深圳市护家科技有限公司 2025-04-24 WO claimed
CN-119841755-A Retinol derivative or its salt, and preparation method and application thereof 深圳市护家科技有限公司 2025-04-18 CN claimed
CN-113150189-A Preparation method of benzophenone photoinitiator 优缔贸易(上海)有限公司 2021-07-23 CN claimed
CN-113024573-A Epodophyllotoxin derivative, preparation method and application thereof in preparation of antitumor drugs 江苏百奥信康医药科技有限公司 2021-06-25 CN claimed
EP-3307395-B1 SOLUBILISING AGENTS FOR UV SCREENING COMPOUNDS ISP INVESTMENTS LLC (US) 2020-08-05 EP claimed
EP-3600224-A1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP Investments LLC (US) 2020-02-05 EP claimed
CN-107366470-B Sisal fiber tent for field taking up quarters cloth 广西师范学院 2019-06-25 CN claimed
WO-2018175836-A1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-09-27 WO claimed
CN-108181388-A A kind of method for differentiating willow type propolis and yang gum 中国农业科学院蜜蜂研究所 2018-06-19 CN claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
CN-1655057-A Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and uses thereof SAMSUNG ELECTRONICS CO LTD (KR) 2005-08-17 CN claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
US-6451334-B2 PULSE ADMINISTERING OF A C1-C4 SUBSTITUTED AND/OR PHENYL SUBSTITUTED CARBOXYLIC ACID AND SALTS AND A CARRIER OR DILUENT TO STIMULATE CELLS IN TREATING BLOOD DISORDERS, E.G. SICKLE CELL ANEMIA, THALASSEMIA, BLOOD LOSS ETC. Perrine, Susan P. 2002-09-17 US claimed
WO-2002015691-A1 USE FOR CONIFER SAPLING PROTECTION AGAINST INSECT ATTACK ROBIGUS AB (SE) 2002-02-28 WO claimed
CN-1030681-C Improvements in or relating to avian control NAT RES DEV (GB) 1996-01-17 CN claimed
EP-0491706-B1 METHOD OF PREPARING A SAMPLE FOR ANALYSIS FINNIGAN MAT LTD (GB) 1995-09-06 EP claimed
EP-0491706-A1 METHOD OF PREPARING A SAMPLE FOR ANALYSIS. FINNIGAN MAT LTD (GB) 1992-07-01 EP claimed
WO-1991004570-A1 METHOD OF PREPARING A SAMPLE FOR ANALYSIS FINNIGAN MAT LTD. (GB) 1991-04-04 WO claimed
CN-1035034-A The improvement of avian control NAT RES DEV (GB) 1989-08-30 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 MAPT 539/4885ALDH1A1 1723/4885MEN1 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.