Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401291 | 0.94 | LMNA (0.38) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL31672289 | 0.90 | SMN1; SMN2 (0.35) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9179159 | 0.87 | LMNA (0.31) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL14719741 | 0.87 | LMNA (0.31) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2118202 | 0.87 | LMNA (0.31) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8832872 | 0.87 | LMNA (0.31) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL28392616 | 0.87 | MEN1 (0.42) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8757561 | 0.87 | MEN1 (0.42) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL225132 | 0.87 | MEN1 (0.42) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL10734238 | 0.86 | LMNA (0.33) | LMNAMEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190264017-A1 | SOLID SUPPORT | LIFE TECHNOLOGIES AS (NO) | 2019-08-29 | — | — | US | claimed |
| US-11041068-B2 | Solid support | LIFE TECHNOLOGIES AS (NO) | 2021-06-22 | — | — | US | disclosed |
| US-20190264017-A1 | SOLID SUPPORT | LIFE TECHNOLOGIES AS (NO) | 2019-08-29 | — | — | US | disclosed |