Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.60 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | RARA | P10276 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28315684 | 0.85 | S1PR2 (0.52) | ALDH1A1S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL28554084 | 0.83 | MAPT (0.60) | S1PR2S1PR1S1PR3S1PR4MAPT | |
| SCHEMBL11291692 | 0.83 | MAPT (0.60) | S1PR2S1PR1S1PR3S1PR4MAPT | |
| SCHEMBL29792919 | 0.83 | MAPT (0.60) | S1PR2S1PR1S1PR3S1PR4MAPT | |
| SCHEMBL7102236 | 0.83 | MAPT (0.60) | S1PR2S1PR1S1PR3S1PR4MAPT | |
| SCHEMBL11294877 | 0.83 | MAPT (0.60) | S1PR2S1PR1S1PR3S1PR4MAPT | |
| SCHEMBL6557873 | 0.83 | RARB (0.51) | ALDH1A1RARBMEN1RARAMAPT | |
| SCHEMBL11288235 | 0.83 | MAPT (0.60) | S1PR2S1PR1S1PR3S1PR4MAPT | |
| SCHEMBL5511989 | 0.83 | MAPT (0.60) | S1PR2S1PR1S1PR3S1PR4MAPT | |
| SCHEMBL7828484 | 0.82 | PPARG (0.50) | ALDH1A1S1PR2S1PR1MAPTSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019161705-A1 | NEW METHOD FOR SYNTHESIZING 1,6-(P-AMIDINOPHENYL)HEXYL DIETHER | 广州同隽医药科技有限公司 | 2019-08-29 | — | — | WO | claimed |
| WO-2019161705-A1 | NEW METHOD FOR SYNTHESIZING 1,6-(P-AMIDINOPHENYL)HEXYL DIETHER | 广州同隽医药科技有限公司 | 2019-08-29 | — | — | WO | disclosed |