SCHEMBL6557873

SCHEMBL6557873

O=C(O)C(CCCCc1ccc(-c2ccc(CCCCC(C(=O)O)C(=O)O)cc2)cc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.51
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
RARA P10276 1/20 0.50
MAPT P10636 1/20 0.50
MTOR P42345 1/20 0.50
KMT2A Q03164 1/20 0.50
HDAC2 Q92769 2/20 0.49
HDAC1 Q13547 1/20 0.47
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP12 P39900 1/20 0.46
MMP13 P45452 1/20 0.46
MMP14 P50281 1/20 0.46
FFAR1 O14842 1/20 0.46
MGLL Q99685 1/20 0.45
MME P08473 1/20 0.45
FDFT1 P37268 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7828484 0.87 PPARG (0.50) ALDH1A1MAPTHDAC2HDAC1FDFT1
SCHEMBL8170321 0.86 MAPT (0.57) MAPTHDAC2HDAC1
SCHEMBL20569893 0.85 PPARA (0.58) HDAC2HDAC1
SCHEMBL11291692 0.84 MAPT (0.60) MAPTHDAC2HDAC1
SCHEMBL11288235 0.84 MAPT (0.60) MAPTHDAC2HDAC1
SCHEMBL5511989 0.84 MAPT (0.60) MAPTHDAC2HDAC1
SCHEMBL29792919 0.84 MAPT (0.60) MAPTHDAC2HDAC1
SCHEMBL11294877 0.84 MAPT (0.60) MAPTHDAC2HDAC1
SCHEMBL7102236 0.84 MAPT (0.60) MAPTHDAC2HDAC1
SCHEMBL28554084 0.84 MAPT (0.60) MAPTHDAC2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490420-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 2004-12-29 EP disclosed
WO-2003082949-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 2003-10-09 WO disclosed