Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.44 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2128731 | 0.91 | GRIN2D (0.48) | PIK3CDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16132005 | 0.88 | GRIN2D (0.47) | PIK3CDUSP30GRIN2DGRIN3BGRIN1 | |
| SCHEMBL13279450 | 0.84 | USP30 (0.47) | USP30GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13466920 | 0.82 | LRRK2 (0.47) | USP30LRRK2 | |
| SCHEMBL16785555 | 0.80 | GRIN2D (0.49) | PIK3CDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17696424 | 0.80 | GRIN2D (0.49) | PIK3CDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16785554 | 0.80 | GRIN2D (0.49) | PIK3CDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18752414 | 0.80 | GRIN2D (0.49) | PIK3CDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17696421 | 0.80 | GRIN2D (0.49) | PIK3CDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27330164 | 0.80 | GRIN2D (0.49) | PIK3CDGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288044-A1 | COMPOSITIONS AND THERAPEUTIC USES OF IKK-RELATED KINASE EPSILON AND TANKBINDING KINASE 1 INHIBITORS | ALZHEIMER'S INSTITUTE OF AMERICA, INC. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20120101079-A1 | SUBSTITUTED 6-AMINO-NICOTINAMIDES AS KCNQ2/3 MODULATORS | GRUNENTHAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101079-A1 | SUBSTITUTED 6-AMINO-NICOTINAMIDES AS KCNQ2/3 MODULATORS | KCNQ2, KCNQ1, KCNQ3 | PIK3CD 1446/4885USP30 4301/4885GRIN2D 562/4885 |
| US-20140288044-A1 | COMPOSITIONS AND THERAPEUTIC USES OF IKK-RELATED KINASE EPSILON AND TANKBINDING KINASE 1 INHIBITORS | CSNK1G1, PRKCE, PHKG1 | PIK3CD 189/4885USP30 787/4885GRIN2D 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.