Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27407816 | 0.81 | — | — | |
| Ether SCHEMBL21409536 | 0.78 | — | — | |
| Ether SCHEMBL25174388 | 0.77 | — | — | |
| Bromide SCHEMBL22750622 | 0.77 | — | — | |
| Ether SCHEMBL28663930 | 0.75 | TSHR (0.35) | TSHRMEN1POLBKMT2A | |
| Ether SCHEMBL21930394 | 0.74 | — | — | |
| Ether SCHEMBL1766220 | 0.74 | ALDH1A1 (0.35) | TSHR | |
| Ether SCHEMBL9814449 | 0.74 | ALDH1A1 (0.35) | TSHR | |
| Ether SCHEMBL5027455 | 0.74 | — | — | |
| Ether SCHEMBL1001468 | 0.74 | ALDH1A1 (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108300408-B | Organic silicon material for packaging LED with high luminous flux maintenance rate | 宁波凯耀电器制造有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-108300408-B | Organic silicon material for packaging LED with high luminous flux maintenance rate | 宁波凯耀电器制造有限公司 | 2020-09-04 | — | — | CN | disclosed |
| WO-2019163282-A1 | FLUORINE-CONTAINING ETHER COMPOUND, FLUORINE-CONTAINING ETHER COMPOSITION, COATING LIQUID, ARTICLE AND PRODUCTION METHOD THEREOF | ＡＧＣ株式会社 | 2019-08-29 | — | — | WO | disclosed |