SCHEMBL21295765

SCHEMBL21295765

[c]1cccc2sc3cc(-c4ccccc4)ccc3c12

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 4/20 0.40
PIK3CA P42336 1/20 0.37
PI4KA P42356 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
F9 P00740 3/20 0.35
GPR3 P46089 1/20 0.32
JAK2 O60674 1/20 0.32
MCL1 Q07820 1/20 0.32
ALOX5 P09917 1/20 0.32
PIK3CG P48736 1/20 0.31
PIM3 Q86V86 1/20 0.31
ALK Q9UM73 1/20 0.31
DHFR P00374 1/20 0.31
TNKS2 Q9H2K2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295746 0.87 LIMK1 (0.40) LIMK1PIK3CAPI4KAPI4KBALDH1A1
SCHEMBL21295885 0.86 LIMK1 (0.43) LIMK1PIK3CAPI4KAPI4KBMAPT
SCHEMBL21295732 0.80 PIK3CD (0.46) PIK3CAPI4KAPI4KBALDH1A1MAPT
SCHEMBL5007 0.79 GPR3 (0.54) LIMK1ALDH1A1MAPTHPGDRAB9A
SCHEMBL10110898 0.78 LIMK1 (0.51) LIMK1PIK3CAPI4KAPI4KBALDH1A1
SCHEMBL12562737 0.78 LIMK1 (0.51) LIMK1PIK3CAPI4KAPI4KBALDH1A1
SCHEMBL4235905 0.77 GPR3 (0.58) LIMK1PIK3CAPI4KAPI4KBALDH1A1
SCHEMBL21300580 0.77 BCL2L1 (0.37) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL22375204 0.75 LIMK1 (0.49) LIMK1PIK3CAPI4KAPI4KBALDH1A1
SCHEMBL18329359 0.75 LIMK1 (0.49) LIMK1PIK3CAPI4KAPI4KBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed