SCHEMBL21295939

SCHEMBL21295939

[c]1ccccc1-c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
GSTP1 P09211 1/20 0.39
CYP1A2 P05177 3/20 0.39
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HBB P68871 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALOX5 P09917 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
CYP11B1 P15538 3/20 0.37
CYP11B2 P19099 3/20 0.37
CYP17A1 P05093 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL948858 0.94 GSTP1 (0.45) ESR1ESR2GSTP1CYP1A2ALDH1A1
SCHEMBL8589112 0.86 ESR1 (0.50) ESR1ESR2CYP1A2CYP3A4ALOX5
SCHEMBL15826005 0.86 ESR1 (0.52) ESR1ESR2GSTP1CYP1A2ALDH1A1
SCHEMBL8591437 0.85 ESR1 (0.52) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL8590691 0.83 CYP2A6 (0.50) ESR1ESR2GSTP1CYP1A2ALDH1A1
SCHEMBL3776601 0.83 CYP1B1 (0.47) CYP1A2ALDH1A1HIF1AHSD17B10TDP1
SCHEMBL8588843 0.82 CYP2A6 (0.48) ESR1ESR2GSTP1CYP1A2ALDH1A1
SCHEMBL28841680 0.81 CYP1B1 (0.48) CYP1A2ALDH1A1HIF1AHSD17B10TDP1
SCHEMBL2452767 0.80 ESR1 (0.46) ESR1ESR2GSTP1CYP1A2ALDH1A1
SCHEMBL28598899 0.80 ALDH1A1 (0.50) CYP1A2ALDH1A1CYP3A4HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557856-A Preparation method for 9,9-diaryl thiophene xanthene-10,10-dioxide UNIV NANJING POSTS & TELECOMM 2015-04-29 CN claimed
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed
CN-109311844-A Triaizine compounds, its manufacturing method and the organic electroluminescent device as constituent 东曹株式会社 2019-02-05 CN disclosed
CN-104557856-A Preparation method for 9,9-diaryl thiophene xanthene-10,10-dioxide UNIV NANJING POSTS & TELECOMM 2015-04-29 CN disclosed