SCHEMBL21295974

SCHEMBL21295974

Cc1[c]cc2c(c1)sc1ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.52
ALDH1A1 P00352 8/20 0.47
MAPT P10636 6/20 0.47
RAB9A P51151 3/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 5/20 0.37
POLB P06746 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
NPC1 O15118 1/20 0.36
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28573918 0.85 GPR3 (0.52) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL5116538 0.79 GPR3 (0.54) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL28316922 0.74 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL9146145 0.73 GPR3 (0.45) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL23917090 0.73 GPR3 (0.78) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL1637414 0.73 GPR3 (0.78) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL30077259 0.73 GPR3 (0.78) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL30451427 0.73 GPR3 (0.78) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL12925865 0.72 GPR3 (0.61) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL31677946 0.72 GPR3 (0.61) GPR3ALDH1A1MAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed