SCHEMBL21295986

SCHEMBL21295986

CC[Si](CCN)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.40
TAAR1 Q96RJ0 6/20 0.34
LOXL2 Q9Y4K0 2/20 0.34
HTR2A P28223 2/20 0.34
CYP2A6 P11509 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HRH1 P35367 1/20 0.32
TP53 P04637 1/20 0.32
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
PRMT8 Q9NR22 1/20 0.31
MAOA P21397 1/20 0.31
ESR2 Q92731 2/20 0.31
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20637289 0.82 ESR1 (0.43) ESR1TP53ESR2AR
SCHEMBL2444645 0.81 ESR1 (0.56) ESR1SMN1; SMN2TP53ESR2AR
SCHEMBL2012877 0.73 MAPT (0.41) ESR1TAAR1LOXL2HTR2ACYP2A6
SCHEMBL17892513 0.72 TAAR1 (0.39) ESR1TAAR1HTR2ACYP2A6MAOA
SCHEMBL10280463 0.72 TP53 (0.38) ESR1TAAR1LOXL2TP53MAOA
SCHEMBL10730048 0.72 ESR1 (0.45) ESR1TP53ESR2AR
SCHEMBL25648078 0.71 TP53 (0.44) ESR1LOXL2TP53
Methylamine SCHEMBL28808165 0.71 ESR1 (0.38) ESR1TP53
SCHEMBL15863411 0.70 ESR1 (0.45) ESR1TP53ESR2AR
SCHEMBL27953360 0.70 ESR1 (0.40) ESR1SMN1; SMN2TP53ESR2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022228449-A1 PREPARATION METHOD FOR POLYIMIDE RESIN AND THIN FILM THEREOF 上海瑞暨新材料科技有限公司 2022-11-03 WO disclosed
WO-2019164068-A1 GRAPHITE SHEET POLYIMIDE FILM COMPRISING SPHERICAL PI-BASED FILLER, MANUFACTURING METHOD THEREFOR, AND GRAPHITE SHEET MANUFACTURED USING SAME 에스케이씨코오롱피아이 주식회사 2019-08-29 WO disclosed