Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988676 | 0.75 | NR1H2 (0.43) | TP53ESR1ESR2ALDH1A1PSIP1 | |
| SCHEMBL9697410 | 0.73 | ESR1 (0.35) | TP53ESR1ESR2ALDH1A1NPC1 | |
| SCHEMBL3889977 | 0.72 | TP53 (0.41) | TP53ESR1ESR2ALDH1A1PSIP1 | |
| SCHEMBL2444645 | 0.72 | ESR1 (0.56) | TP53ESR1ESR2ALDH1A1PSIP1 | |
| SCHEMBL21295986 | 0.72 | ESR1 (0.40) | TP53ESR1ESR2LOXL2TAAR1 | |
| SCHEMBL121702 | 0.72 | SMN1; SMN2 (0.37) | ALDH1A1LTA4HMAPT | |
| SCHEMBL12191013 | 0.70 | ESR1 (0.41) | TP53ESR1ESR2ALDH1A1PSIP1 | |
| SCHEMBL9226507 | 0.70 | MAPT (0.45) | TP53ESR1ESR2ALDH1A1PSIP1 | |
| SCHEMBL2329848 | 0.70 | NR1H2 (0.47) | TP53ESR1ESR2ALDH1A1PSIP1 | |
| SCHEMBL20637391 | 0.70 | NR1H2 (0.42) | TP53ESR1ESR2ALDH1A1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |