Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586026 | 0.87 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL2754706 | 0.87 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL4578793 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL14780181 | 0.82 | TSHR (0.45) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL3451996 | 0.81 | TSHR (0.42) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL10279957 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL11059576 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL7855289 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL5437406 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4POLBADORA3 | |
| SCHEMBL17874040 | 0.79 | TSHR (0.43) | ALDH1A1TSHRCYP3A4POLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200376130-A1 | COMPOUNDS AND METHODS USEFUL IN BRACHYTHERAPY | NORTH CAROLINA STATE UNIVERSITY | 2020-12-03 | — | — | US | disclosed |
| WO-2019165171-A2 | COMPOUNDS AND METHODS USEFUL IN BRACHYTHERAPY | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200376130-A1 | COMPOUNDS AND METHODS USEFUL IN BRACHYTHERAPY | FOLH1, DNPEP, UNG | ALDH1A1 230/4885TSHR 1681/4885CYP3A4 2884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.